| abstract |
The present invention relates to a compound of the formula (1), pharmaceutically acceptable salt, physiologically hydrolysable ester, hydrate, solvate, or steroisomer thereof having inhibitory activity against caspases. The compound contains unknown new 2-alkyl-4-oxobutanoyl group. Further, the present invention relates to a process for preparing the compound of formula 1 and a method for determining its binding ability for caspases. The compound of formula 1 can be used effectively for the treatment or relief of various diseases caused by caspases. |