| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08e05b0b33b64adc7b87382801ba40b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9284e6599c8ddde900744edd6d9e8545 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-355 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- |
| filingDate |
2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_212bb38a31c0923edbba5b088d1ba81a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_117384ceab4c1edc8b7f9363367f51ec |
| publicationDate |
2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005033290-A2 |
| titleOfInvention |
Methods for altering mrna splicing and treating familial dysautonomia and other mechanistically related disorders |
| abstract |
This invention relates to methods for altering the splicing of mRNA in cells. In particular, this invention also relates to methods for increasing the ratio of wild type to misspliced forms of mRNA and corresponding encoded proteins in cells possessing a mutant gene encoding either the i) misspliced mRNA corresponding to the mutant protein or ii) a component in the splicing machinery responsible for processing the misspliced mRNA. In addition, this invention relates to treating individuals having a disorder associated with a misspliced mRNA, such as Familial Dysautonomia or Neurofibromatosis 1, by administering to such an individual a cytokinin such as kinetin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I727939-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3244891-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016206589-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4115882-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016115434-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11702417-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2020277224-B2 |
| priorityDate |
2003-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |