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filingDate 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b65beab4602fa336f75ef006a700e2ad
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publicationDate 2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005033147-A1
titleOfInvention Interacting polypeptide comprising a heptapeptide pattern and a cellular penetration domain
abstract The invention relates to an interacting polypeptide consisting of or comprising a heptapeptide pattern of sequence X1X2X3X4X5X6X7 and a transduction domain, characterized in that it is a chimera polypeptide, the amino acid X7 is located between 5 and 35 amino acids of the C-terminal end of said polypeptide, and that the domain (b) is situated in C-terminal relative to pattern (a). The invention also relates to screening methods for identifying interacting polypeptides capable of modifying the phenotype of a cell and to uses of interacting polypeptides as mentioned in phenotypic screens or for therapeutic purposes. Lastly, the invention concerns interacting polypeptides capable of modifying the function of the HIV-1 Rev viral protein.
priorityDate 2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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