Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_445c41fa7e8e8a1635660b16fa6f7fde http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01dfac2cd07f2a5222250d75ce4ac269 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51d028c578ae85cb937b5b34a5129fbc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-629 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-632 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-656 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-00 |
filingDate |
2004-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d2da564f89cd308bbd050b93bd2d7ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd7d1050747131c696b7c757a1424102 |
publicationDate |
2005-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005030997-A1 |
titleOfInvention |
Methods and device for dna sequencing using surface enhanced raman scattering (sers) |
abstract |
The methods and apparatus disclosed herein concern nucleic acid characterization by enhanced Raman spectroscopy. In certain embodiments of the invention, exonuclease treatment of the nucleic acids results in the release of nucleotides. The nucleotides may pass from a reaction chamber through a microfluidic channel and enter a nanochannel or microchannel. The nanochannel or microchannel may be packed with nanoparticle aggregates containing hot spots for Raman detection. As the nucleotides pass through the nanoparticle hot spots, they may be detected by Raman spectroscopy. Identification of the sequence of nucleotides released from the nucleic acid is used to characterize the nucleic acid, for example by sequencing or identifying the nucleic acid. Other embodiments of the invention concern apparatus for nucleic acid sequencing. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7605916-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008539711-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008036939-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9562809-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1706508-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8372629-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008036939-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012043028-A1 |
priorityDate |
2003-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |