Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c5c45e2e635fb9bb871d5a32148190c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b11b3319bb4fc55e9bdb51bb8b4c86e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92c68df06ef0131e022649bd279738d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f578a781d25d5e0eecabe9e47d2649c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4bc26a3106345aa99c080bf449a4250 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6933 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
filingDate |
2004-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84f946e9d01e1a2a209cc000df779b0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7137c83fbb4bd8d30e67d6ba63551a69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ad2f15a5bb507bd5a3fdf7dfd9bef11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66df1a52870e3ab8fe84babefad3c119 |
publicationDate |
2005-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005030126-A2 |
titleOfInvention |
Adhesin-specific nanoparticles and process for using same |
abstract |
The present invention is generally directed to compositions useful in preventing and/or treating disease due to infection by any of a variety of biologically active pathogenic microorganisms. The compositions include nanoparticles formed of a hydrophobic polymeric core, hydrophilic linking agents bound to the core, and biofunctional materials bound to the linking agents. The biofunctional materials are functionally identical to receptors on host cell surfaces that can be recognized and bound by adhesins on the surface of the targeted pathogenic adhesin-bearing microorganisms. In one embodiment, the binding action between the nanoparticles and the microorganisms can lead to the formation of large agglomerated complexes, which can then be easily removed from an area, including the digestive tract of an infected individual. The compositions of the present invention can also be utilized in preventing enteric infections via the ability to purge animals of enteropathogens prior to transport and processing for human consumption. |
priorityDate |
2003-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |