Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3ee0e8da7630157820c5d9d65243032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2690e09b2002603cfa39574451c72a58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55bc2bae9f65cfaede67b62128f00e9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb6f89c9ae1a7b06ae2c37599d6180ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d820fad0750a49c872320b596115127f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_827c1232fcbf541c157d15d9debe76a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2fed50fe744687ccdd0e2d77836a24d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f0baf1fac95fc58712ae0d32ab8bee0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-912 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6843 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2004-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171aaf115ebf03f6957ce2456da90eb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd5785ec4d06fb71192561da6fc6dfd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a9de89cda8fb1a4237916d674796d86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd45faddfecd4a37294633602e8e3c26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fabcea63ba6f7aebe71a7aae64d17c69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f1f882c11884c38cc61fa3ed22e18b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d417d6ae1d4a31231e09696a0aa52d93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_989065e8fc62960adede3a631b137eab |
publicationDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005029066-A3 |
titleOfInvention |
Diagnostic markers and pharmacological targets in heart failure and related reagents and methods of use thereof |
abstract |
The invention identifies genes whose expression is upregulated or downregulated following mechanical offloading in subjects with heart failure. The invention provides compositions comprising a targeting agent conjugated to a functional moiety, wherein the targeting agent selectively binds to a polypeptide encoded by one of these genes. The functional moiety can be an imaging agent, therapeutic agent, etc. The invention further provides methods for providing diagnostic or prognostic information related to heart failure involving detecting expression or activity of an expression product of one or more of the identified genes. The invention further provides diagnostic and therapeutic methods comprising detecting or administering an apelin peptide to a subject. |
priorityDate |
2003-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |