| abstract |
The present invention relates to a process for preparing enteric water-dispersible hydroxypropyl methylcellulose phthalate nanoparticles, in particular, to a process for preparing enteric water-dispersible hydroxypropyl methylcellulose phthalate nanoparticles in a cost-effective and time-saving manner, in which hydroxypropyl methylcellulose phthalate nanoparticles are prepared without using an emulsifier, wherein the residual electrolyte content is adjusted through ion exchange step for a short period of time followed by the addition of a plasticizer, thereby the environment-friendly water-dispersible hydroxypropyl methylcellulose phthalate nanoparticles showing excellent film properties and enteric coating properties are prepared. |