http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005024053-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a17d561a57b7b3c1a059f809c34f5e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16bbd96844535f7c6d44e9309d36796e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ca30a154cdb88d5f6b01ba5f7f92fcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b167459d83e588d7504a8b048163687 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2004-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dfcd697e08d16dfba281c33e4be40c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beaa2858f45da0b36d52d19b9f9530be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_309364ddda105a108850a7dab8566ef6 |
| publicationDate | 2005-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2005024053-A1 |
| titleOfInvention | Nucleic acid detection assay |
| abstract | A method for determining the methylation status of a potential methylation site in genomic nucleic acid comprising treating genomic nucleic acid with an agent which modifies cytosine bases but does not modify 5methyl-cytosine bases under conditions to form a. modified nucleic acid template containing a potential methylation site; providing a first clamp containing a first capture sequence complementary to a region flanking one side of the potential methylation site in the modified nucleic acid template, providing a second clamp containing a second capture sequence complementary to a region flanking the other side of the potential methylation site in the modified nucleic acid template; allowing the first clamp and the second clamp to hybridise to the modified nucleic acid template; ligating the hybridised first and second clamps to form a probe spanning the potential methylation site in the modified nucleic acid template; digesting the modified nucleic acid template to obtain the probe; and detecting the probe and determining the methylation status of the potential methylation site in the modified genomic nucleic acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013107287-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8771939-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9850533-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005108618-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112752853-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102559661-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7364855-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005108618-A2 |
| priorityDate | 2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.