| abstract |
The invention relates to a coexpression vector for the membrane domains of virus envelope proteins and to a method for the production of homooligomers and/or heterooligomers of said domains. The vector comprises at least one replication and maintenance area for said vector in the host cell; a first region which, in the direction of translation of said vector, is succesively comprised of a first promoter followed by a first sequence coding for a first chimeric protein comprising, in particular, a sequence coding for one of the at least two membrane domains; and a second region which, in the direction of translation of said vector, is successively comprised of a second promoter followed by a second sequence coding for a second chimeric protein comprising, in particular, a sequence coding for the other membrane domain of the at least two membrane domains. The invention can be more particularly used in the production of a medicament for the treatment of or for the prophylaxis of Hepatitis C. |