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filingDate 2004-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fc605f74ec1cc8f11c6da60d313f3b1
publicationDate 2005-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005019451-A1
titleOfInvention Nucleic acid construct for expressing pdk-1 activity inhibitor
abstract It is intended to provide a means of regulating the phosphorylation activity of PDK-1 and a means of treating diseases caused by disorder in this activity. A nucleic acid construct for expressing an inhibitor of 3-phosphoinositide-dependent protein kinase 1 activity which contains a nucleic acid encoding a substance capable of inhibiting the activity of the phosphoinositide-dependent protein kinase 1 in vivo; a support for the expression of an inhibitor of 3-phosphoinositide-dependent protein kinase 1 activity in a mammalian cell which carries the nucleic acid construct for the expression as described above; a remedy and a therapeutic method for diseases caused by disorder in the phosphorylation activity of 3-phosphoinositide-dependent protein kinase 1 which contains the nucleic acid construct for the expression as described above or the support for the expression as described above as the active ingredient; and the nucleic acid construct for the expression as described above or the support for the expression as described above aiming at the production of a medicinal composition for the above diseases.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013109142-A1
priorityDate 2003-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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