Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_672c7f08fab3c43db9596f447b3cc294 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d5214d9c29dce76d6efa46971e3e0aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e5c121269689cbab9b3a4548b15caf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67dec9c734ccb88beb9fe24653d7f3a7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2004-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e598e6cca030a3f2e3986af0aaeeaba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df9166099f1ff519a40ca6285bdfda73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84a5552fdfff7dc33529556d4d275ae3 |
publicationDate |
2005-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005018673-A1 |
titleOfInvention |
Pharmaceutical composition for preventing or remedying cardiac hypertrophy and cardiocascular disease caused thereby |
abstract |
The present invention is based on the discovery that protein D1 that is broadly present in the human body plays a central role in the signal cascade that induces hypertrophy in cardiomyocytes. Concretely, the present invention provides pharmaceutical compositions for suppressing cardiac hypertrophy and compositions that can be used to prevent or remedy heart disease caused by cardiac hypertrophy. The present invention further provides a method to suppress the onset and development of cardiac hypertrophy in patients with cardiac hypertrophy or the pre-conditions thereof and a method for screening active ingredients of the above-mentioned compositions, and animal models of cardiac hypertrophy . |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8058268-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8143445-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9079917-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8227473-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8329719-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10023587-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8455688-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10399993-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9580515-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7998957-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014221042-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11253573-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9526915-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014001243-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227418-B2 |
priorityDate |
2003-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |