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publicationDate 2005-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005016877-A3
titleOfInvention Pyrazole carboxamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
abstract Pyrazole carboxamides of structural formula (I) are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.
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