| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0f7e6bb843e20152cf528153620bd5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d5ae17bbf781c6bdbb0791e2a12a9c9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2004-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a756dd11df7cc3bc0a4ab15dc4ca1376 |
| publicationDate |
2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005016274-A2 |
| titleOfInvention |
Rnai treatment of eye disease |
| abstract |
The present invention relates to RNA interference (RNAi) for preventing or reducing the expression of the thyroid stimulating hormone receptor gene in a target cell. In particular, the present invention provides compositions comprising small interfering RNA duplexes (siRNAs), or vectors that encode SIRNA, that inhibit the expression of the TSHr gene (e.g. by targeting TSHr mRNA), and methods of using these compositions to treat or prevent eye disease (e.g. Graves’ ophthalmopathy) in a patient. |
| priorityDate |
2003-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |