| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c2e96287aa88875cd7333f2c3600eec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a5c90c8948d48ed7f60962f1b2d2b2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-254
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30586
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30677
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-622 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate |
2004-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72c130af34f732e9930301ff98e32b4f |
| publicationDate |
2005-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005014071-A1 |
| titleOfInvention |
Methods and devices for the treatment of intervertebral discs |
| abstract |
Devices for the treatment of intervertebral discs are described. The devices, when implanted into the nucleus pulposus of an intervertebral disc, provide for the controlled release of one or more active agents into the disc. The active agent can be a chemonucleolytic agent such as chymopapain. The device can also comprise one or more binders. The device can be an elongate solid body having a tapered or rounded insertion end. Alternatively, the device can include a plurality of particles. For devices containing multiple active agents, the configuration of the device be chosen to provide for the sequential or simultaneous release of each of the active agents. The elongate solid body can include a sheath comprising a first active agent and a core comprising a second active agent. Methods of making the devices and methods of treatment comprising implanting the devices into an intervertebral disc are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101605534-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102940878-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9061064-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008040557-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010505482-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8642059-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8920828-B2 |
| priorityDate |
2003-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |