Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10552ab7c2a2877364c90b839abbd332 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_360ea0ce5e2c7005f0acd2f1d9d26bd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6888bfa61a7cae27386edcfa9fe7298 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5030b89518615d577a0fe3582c3c4fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de04b5bf7946d2489e6ec99e1c99907d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd3129dacf390048837709823830969f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
filingDate |
2003-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d5bc89471ebe6db51575b596f4d3c84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_366f0c1bac20a17a5b63c52b9295665b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3edc531290c20a088ae89a040aeef76d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c61dfabe157ae6d66cf854e5896c5f3d |
publicationDate |
2005-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005014015-A1 |
titleOfInvention |
Compositions containing macrophages and uses thereof |
abstract |
The invention relates to the use of macrophages for the preparation of a drug for the treatment of a disease or of a lesion involving cellular apoptosis, reduction of the survival of cells and/or destruction of cells. The present invention also provides the use of macrophages for the preparation of a drug for the improvement of survival of a first type of cells, for the treatment of a disease or of a lesion involving the destruction of a second type of cells or of a tissue containing a second type of cells, said first type of cells being chosen among the group consisting of: precursor cells, stem cells and any type of differentiated cells. The inventors surprisingly showed that macrophages may inhibit precursor cells apoptosis in a cell to cell contact and may serve as stromal support for efficient cellular engraftment for tissue repair. They showed in particular that macrophages could inhibit myogenic precursor cell apoptosis. |
priorityDate |
2003-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |