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filingDate 2004-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005012554-A1
titleOfInvention On-chip bioassy method and kit
abstract A highly versatile on-chip bioassay system in which analysis can be carried out with high throughput while lessening preoperation, e.g. incubation. A micro fluid chip for introducing cells is bonded to the lower surface of a fine hole chip composed of a substrate through which a plurality of fine holes penetrate while being arranged in lattice thus forming a plurality of fine channels between the fine hole chip and the micro fluid chip for introducing cells. Suspended cells are fed into the fine holes through the channels and a micro fluid chip for introducing a substance being inspected is bonded to the upper surface of the fine hole chip such that its plurality of fine channels for introducing the substance being inspected intersect the channels for introducing cells perpendicularly thus forming a plurality of fine channels between the fine hole chip and the micro fluid chip for introducing the substance being inspected. The substance being inspected is fed through these channels and touched to the cells in the fine holes of the fine hole chip and after elapsing a specified time, or at a specified time interval, the degree of effect of the substance being inspected onto the cell is detected in situ.
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