| abstract |
The present invention relates to agents that modulate HAAH activity by immunospecifically binding to HAAH on the surface of the mast cell. More specifically, this invention provides HAAH antagonists that modulate mast cells. Also provided are methods for the prevention, management, treatment, or amelioration of respiratory conditions, an inflammatory or autoimmune disorder or cardiovascular disease, said methods comprising administering to a subject in need thereof an effective amount of one or more agents that modulate the activity of HAAH. |