| abstract |
The invention relates to a method of obtaining taxosteroids and the precursors thereof from hydrindane bicyclic systems. According to the invention, the compounds have a tetracyclic system which combines the structural characteristics of: taxanes, such as the bicyclic[5.3.1]undecane system (cycles A and B) which is fused to a ring with six members (C), and steroids, such as the CD-bicyclic system, the A ring and side chain (Sc). The invention also relates to the method of preparing said compounds and to the use thereof as compositions with beneficial pharmacological properties. |