| abstract |
Cancer-linked gene sequences, and derived amino acid sequence, are disclosed along with methods for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes, for the SOX11, expressed in cancers of brain, breast and lung. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosis of cancers using the disclosed gene sequences. |