| abstract |
Immunogenic compositions and methods for eliciting an immune response against B. anthracis and other bacilli are provided that include immunogenic conjugates of a poly-Ϝ-glutamic acid (ϜPGA) polypeptides of B. anthracis, or of another Bacillus that expresses a ϜPGA polypeptide. The ϜPGA conjugates elicit an effective immune response against B. anthracis, or against another Bacillus, in mammalian hosts to which the conjugates are administered. The preferred conjugate consists of Ϝ-D-PGA and Bacillus protective antigen. |