http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004113302-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19229fe7f5fcc0a484adc464fc5bdb8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db3839a005f23c9828fe42bb0e030303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b63590c5f7c2c6fa4b79d4df239a36cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63ce66f54d5ecc61ee76da3f52b45e33 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 |
filingDate | 2004-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b522cd29b9851df0ea8422c4e4bf014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64e4d4091f78960ca89d425f71e1e283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddf3ffeeae262f01c4b6c0a0490ce71b |
publicationDate | 2004-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2004113302-A1 |
titleOfInvention | N-substituted 6,8-dialkoxy-1,2,3,4-tetrahydro-1h-isoquinoline as potassium channels modulators |
abstract | The invention relates to compounds having the Formula (I) or a salt, or a physiologically functional derivative, or a prodrug thereof, (I) wherein Z is carbonyl or sulfonyl; R1 is alkyl, alkenyl, alkynyl, aryl, H, halogen, haloalkyl, haloalkoxy, hydroxyalkyl, cycloalkyl or heteroaryl; R2 is H, OH, -CH2-SO2-alkyl, -CH2-SO2-cycloalkyl, -CH2-SO2-aryl, -CH2-SO2-heteroaryl, alkylamine, alkenylamine, alkynylamine, cycloalkylamine, arylamine, heteroarylamine, aryl, haloalkyl, haloalkoxy, hydroxyalkyl, cycloalkyl, heteroaryl or a linear or branched alkyl, alkenyl, alkynyl, which can optionally be substituted by one or more substituentes R3; R3 is H, alkyl, alkenyl, alkynyl, cycloalkyl, -CO2R4, -CONHR4, -CONR4R4, - CR4O, SO2R4, -NR4-CO-R4, alkoxy, alkylthio, -OH, -SH, -O-aryl, -O-cycloalkyl, -S-aryl, -S-cycloalkyl, hydroxyalkyl, halogen, haloalkyl, haloalkoxy, CN, NO2, hydroxyalkylamine, aminoalkyl, alkylamine, aryl or heteroaryl; R4 is H, halogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylthio, -O-aryl, - O-cycloalkyl, OH, SH, -S-aryl, -S-cycloalkyl, hydroxyalkyl, haloalkyl, haloalkoxy, hydroxyalkyl-amine, aminoalkyl, alkylamine, aryl or heteroaryl; R5 is alkyl, alkenyl or alkynyl. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008528526-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4829900-B2 |
priorityDate | 2003-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 547.