Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c39fd8026c719c970650e5ce6b04fc08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_896b038532052a4738c23b5352422772 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba3b05dcaaa876d8a4e4700db8f765c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e68831fd7a18aca55fb4556e3277ad6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0406 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
filingDate |
2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_286c150fb1b613d0f647373785c2a4c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab9fdaa3483b23ec218e4c6830dc81b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76cdc91e33d37587728e483282814f31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_181061387c86991ae53fd2781d2e27c5 |
publicationDate |
2005-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004110963-A3 |
titleOfInvention |
Glycerophosphocholine and its derivatives for medical imaging neuropsychiatric disorders |
abstract |
Compounds, compositions and methods for the diagnosis of Alzheimer's disease. Synthesized Glycerophosphocholine (GPC) may be used as a diagnostic aid to measure progression of Alzheimer's disease. GPC is a membrane phospholipid metabolite that is capable of binding specifically to the β-turn of beta amyloid (Aβ) peptide. Compounds including non-radioactive, paramagnetic, and radioactive derivatives of GPC are presented. These compounds possess similar binding properties to original GPC molecules and are useful in medical magnetic resonance imaging and/or positron emission tomography applications. By employing these radiological techniques in conjunction with the compositions of the present invention, the diagnosis and assessment of the progression of Alzheimer's disease may be achieved. |
priorityDate |
2003-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |