Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e68831fd7a18aca55fb4556e3277ad6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_896b038532052a4738c23b5352422772 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c39fd8026c719c970650e5ce6b04fc08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba3b05dcaaa876d8a4e4700db8f765c9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_181061387c86991ae53fd2781d2e27c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76cdc91e33d37587728e483282814f31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_286c150fb1b613d0f647373785c2a4c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab9fdaa3483b23ec218e4c6830dc81b7 |
publicationDate |
2004-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004110963-A2 |
titleOfInvention |
Glycerophosphocholine and its derivatives for medical imaging neuropsychiatric disorders |
abstract |
Compounds, compositions and methods for the diagnosis of Alzheimer's disease. Synthesized Glycerophosphocholine (GPC) may be used as a diagnostic aid to measure progression of Alzheimer's disease. GPC is a membrane phospholipid metabolite that is capable of binding specifically to the β-turn of beta amyloid (Aβ) peptide. Compounds including non-radioactive, paramagnetic, and radioactive derivatives of GPC are presented. These compounds possess similar binding properties to original GPC molecules and are useful in medical magnetic resonance imaging and/or positron emission tomography applications. By employing these radiological techniques in conjunction with the compositions of the present invention, the diagnosis and assessment of the progression of Alzheimer's disease may be achieved. |
priorityDate |
2003-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |