http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004108750-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_269b0b2f24ff2790756289fa3ac1b9fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c42ade9855ee23eec771e42cfa4010e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08ad81e6123e0cc1612f675963a6808f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1136 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 |
| filingDate | 2003-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b8f0da456cf19ff7b0e71a6431031c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f07420fbf5c2d234718db47071c862e |
| publicationDate | 2004-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2004108750-A1 |
| titleOfInvention | Process for the separation of proteins |
| abstract | There is provided for the separation of one or more protein(s) contained in host cells comprising isolating the protein(s) and solubilising, unfolding and refolding the isolated protein(s) wherein an effective amount of a non-ionic surfactant is introduced during the solubilising, unfolding or refolding. Preferably, the protein(s) which may be separated from host cells by the process of the present invention include bacterial and plant derived toxin protein(s), or analogues thereof. Non-ionic surfactants that may be employed in the process include alkyl and alkaryl capped polyoxyalkylenes, particularly alkyl and alkaryl capped polyoxyethylenes, mixed polyoxyalkylene, particularly polyoxyethylene-polyoxypropylene-polyoxyethylenes, and polyoxyalkylene sorbitan carboxylates, particularly polyoxyethylene sorbitan carboxylates. Advantageously, the protein(s) and compositions comprising protein(s) and non-ionic surfactant obtainable by these processes show improvement in the ability to stimulate an immune response. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9469849-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466262-B2 |
| priorityDate | 2003-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.