Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9feb77efefb8b75f92467b56db0a557f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae9d3d95dde584b33a9e5d448e599438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35dbc60da9891d57c4047fb7b8689516 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41661e6fdf645b3630fbbc7aa92499bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1418e512493aaf5dc69a8ef9f1246bee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 |
filingDate |
2004-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eed05c5cd451e55c1daf9e7daf2f7491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1093180d8e0857874883e1e5bdda2f7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ff0fdccc9ee95f08804fcc20f001f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a49abdc778e46eefcebe6f7833bb07 |
publicationDate |
2004-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004106939-A2 |
titleOfInvention |
Method for the linkage of bifunctional chelating agents and (radioactive) transition metal complexes to proteins and peptides |
abstract |
The present invention relates to a method for radioactive labeling of a protein or peptide, by providing a protein or peptide having at least one glutamine or lysine residue; adding a metal chelating agent having at least one lysine or glutamine residue, respectively, which metal chelating agent is optionally complexed with a radioactive or paramagnetic metal; reacting the protein or peptide and metal chelating agent in the presence of a transglutaminase to obtain a protein or peptide with a metal chelating group covalently bound thereto, and optionally complexing the metal chelating group with a radioactive or paramagnetic metal. The invention also relates to proteins and peptides thus labeled and to proteins and peptides that have been coupled to a metal chelating agent but not yet labeled. |
priorityDate |
2003-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |