Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afafcdaa7d2da0429ed9e040cba1d507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca323f154166c72a01982afd5ddbf7e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8cb90cc732d9646ae9384a946d93c0a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9b8298b511864cf4303d798047de592 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd58fe63c2cfb2e5b04d4916e7327258 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-83 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 |
filingDate |
2004-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2eb31c13adbc9e8de622f43858476a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ada359609485fd66fb750d8b7651a02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34e156438a4fc12158183b430cbd8ba2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c78c71ab58ee38f14936c985e3d1d3ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60713c71cdc56d70969afab940577543 |
publicationDate |
2005-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004101494-B1 |
titleOfInvention |
Calpain inhibitors |
abstract |
The invention relates to compounds comprising a peptide-biphenyl hybrid structure and to associated compounds having a calpain inhibitor activity. One of the inventive compounds is a 2,2'-disubstituted biphenyl, with the substituents at positions 2 and 2' of the biphenyl skeleton being chains containing structures that are associated with amino acids, peptides and amides, which can be identical or different. The invention also relates to all of the conformational isomers (atropisomers) of the aforementioned compound having formula I. Compounds having formula I can be used for the preventive or therapeutic treatment of a degenerative disease. |
priorityDate |
2003-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |