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filingDate 2004-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2eb31c13adbc9e8de622f43858476a
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publicationDate 2005-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2004101494-B1
titleOfInvention Calpain inhibitors
abstract The invention relates to compounds comprising a peptide-biphenyl hybrid structure and to associated compounds having a calpain inhibitor activity. One of the inventive compounds is a 2,2'-disubstituted biphenyl, with the substituents at positions 2 and 2' of the biphenyl skeleton being chains containing structures that are associated with amino acids, peptides and amides, which can be identical or different. The invention also relates to all of the conformational isomers (atropisomers) of the aforementioned compound having formula I. Compounds having formula I can be used for the preventive or therapeutic treatment of a degenerative disease.
priorityDate 2003-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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