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publicationDate 2004-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2004099444-A2
titleOfInvention Diagnostic methods
abstract A method for detecting a strain of Staphylococcus aureus which has reduced susceptibility to vancomycin and/or teicoplanin, said method comprising detecting the level of expression of an fmtB/mrp or mrp-homologue gene or a variant thereof within said strain and relating that to the susceptibility or resistance of the strain to vancomycin and/or teicoplanin. Detection of expression is suitably carried out using immunological to detect the gene product or molecular methods to detect RNA constructs. The method allows for the detection of strains of Staphylococcus aureus that are homogeneously or heterogeneously intermediate to vancomycin and/ or teicoplanin.
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