abstract |
This current invention includes compositions and methods of nitric oxide synthase inhibitors to treat or reduce ischemia/reperfusion injury in a patient. More specifically, the invention relates to a combinational therapy of 5-Aminoimidazole-4-carboxamide-l-B-D ribonucleoside (AICAR) and N-acetyl cysteine, (NAC) to attenuate ischemia/reperfusion injury to a transplanted organ. |