http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004097026-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4750d99e2c1f6f04d2e47f779d13bf03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_548192860294ffc2aac43314f184a7f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df1df309a415a9465769bee7a687b213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba424cfc324c087e5e0782f9be3823be |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
filingDate | 2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f5aa7ad5f656ae3bf748368c65ba45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f246618fac8bf7b521348a3b57c48487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35dad9f02fdfd7cbd2dd1e864a5e1fa8 |
publicationDate | 2005-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2004097026-B1 |
titleOfInvention | The enzymatic method of making 1,2-diol derivatives and their esters |
abstract | The present invention relates to a new process for the preparation of optically active alcohols represented by the general formula 2 and their esters represented by the general formula 3 by enzymatic method from racemic alcohols represented by the general formula 1 in scheme 1. In more details, this invention relates to a process for producing optically active alcohols and their esters which are used as pharmaceutical intermediates from alcohols represented by the general formula 1 by stereospecific transesterification of secondary hydroxyl group using lipases as catalyst with acyl donors in organic solvent or with acyl donors only without using organic solvent. According to this invention, optically active alcohols and esters of high optical purity in high yield can be produced by transforming the primary hydroxyl group of 1,2-diols by tosyl group and transesterifying the secondary hydroxyl group stereospecifically by lipase. |
priorityDate | 2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.