Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9ad96c570f17739c2a74d8f9b856b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23fb3772a662150ca5702eea31bac480 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c4aaad16ebfb87f2db829bab35cae6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd8b0e4007fe2d68e32f9f174b5bfcd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0312 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8114 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0339 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2004-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a93a9c4a360e7ed51fdd9b4fb2875da9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2734f1963f3dc9a1fa6cc93316c9cac7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_757f058af69bb8c478132ba20c78302d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a18bf71ba476c2e3b5900c23b1d92f3d |
publicationDate |
2004-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004093830-A2 |
titleOfInvention |
Model for neurodegenerative disorders |
abstract |
The present invention discloses a double transgenic fly that expresses both human Tau protein and the human Aβ42 peptide of human amyloid-β precursor protein (APP). The double transgenic flies of the present invention display a synergistic altered phenotype as compared to the altered phenotype displayed by transgenic flies expressing either human Tau or human Aβ42 alone. Thus, the flies provide for models of neurodegenerative disorders, such as Alzheimer's disease. The invention further discloses methods for identifying therapeutic compounds to treat neurodegenerative disorders using the double transgenic flies. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2028932-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2028932-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8609361-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009539406-A |
priorityDate |
2003-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |