Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc4a5af22f6763f2c19dbb22849a19dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1de1d17ee8ddd8e9d3acc61125d523fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ca31e1272064f73af41e7d4b45c6585 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 |
filingDate |
2004-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf5529ef22b3d6f4b2599eba9264154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f43efba6e8833cf0e1541f1fb31448eb |
publicationDate |
2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004092387-A1 |
titleOfInvention |
Viral vectors expressing fusion of viral large envelope protein and protein of interest |
abstract |
The present invention provides a virus-like particle (VLP) comprising i) a polypeptide comprising a polypeptide of interest (POI) and at least a particle-associating portion of a large envelope (L) polypeptide of an avian hepadnavirus or a functional derivative or homolog thereof, and ii) a small envelope (S) polypeptide of an avian hepadnavirus or a functional derivative or homolog thereof. By introducing one or more POIs into the L polypeptide, the POI is translocated along with L into a particle structure made up primarily of S polypeptide. The present invention furthermore provides methods for producing a recombinant virus-like particle. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102414313-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008025067-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2007291936-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9309536-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010125201-A1 |
priorityDate |
2003-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |