http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004087187-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23a060c17409e5afad39cb2c8cc589ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2bfa4f5597ec78d8f5276fb27a83d91f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bceffddb90b9b3da8a772212961764b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-02 |
| filingDate | 2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7846006ae43e7cc9d0792923a232fda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3df7ee1ba3d5d556e2c31e4bacc5edb |
| publicationDate | 2004-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2004087187-A1 |
| titleOfInvention | Method of enhancing autoimmunity |
| abstract | It is intended to provide a novel method of enhancing autoimmunity by administering a specific active ingredient which would not lose its activity of binding to a saccharide even by heating, has an excellent capability of selectively recognizing a sugar chain and exhibits an activity of enhancing autoimmunity, for example, activating cellular immunity. The above-described active ingredient is obtained by extracting a red algae belonging to the genus Gracilaria with an aqueous salt solution, carrying out first-stage salting out by adding ammonium sulfate to the liquid extract to give a final concentration of 20 to 40% saturation, removing contaminants thus precipitated, carrying out second-stage salting out by adding ammonium sulfate to the extract to give a final concentration of 60 to 80% saturation, collecting a crude active fraction as the precipitate, and then dissolving the precipitate in an appropriate solvent to give a liquid crude active fraction. If desired, the obtained liquid crude active fraction is heated to 100°C for 1 to 10 minutes to thereby remove contaminating proteins therefrom. Then, the residue is subjected to gel filtration chromatography to give a fraction of molecular weight of 100,000 or more, and further fractionated by chromatography. Then a fraction showing an activity to activate cellular immunity is collected to give the desired active ingredient. |
| priorityDate | 2003-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.