Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5c6e82487d9641d69a35f41fc348662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d947fae7298760ff00c7be3059109cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e19741e967ed6c909c17813b4f9ef63e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B41-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B41-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-10 |
filingDate |
2004-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6a82e7b3394622b99d30e4e61c4c9e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c746c56d4b3de16813d27c26dfce29c |
publicationDate |
2004-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004085344-A2 |
titleOfInvention |
Production of oxy-michael adducts |
abstract |
The invention provides a method of producing an oxy-Michael adduct comprising allowing a Michael acceptor to react with an alkoxide of an alcohol of formula R10H having a chiral centre at the hydroxy carbon, in the presence of a multidentate ligand. The use of the multidentate ligand significantly increases stereoselectivity of the reaction. In a further aspect the multidentate ligand is not essential but the R1 group is removed from the oxy-Michael adduct by acidic solvolysis. In a further aspect in which the multidentate ligand is not essential the alcohol R10H is a lactol. |
priorityDate |
2003-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |