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filingDate 2003-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2004082378-A1
titleOfInvention Method of inhibiting freeze concentrating of substance in wet material, method of inhibiting deactivation of physiologically active substance, and process for producing lyophilizate or frozen matter having component homogeneously diffused therein
abstract When in the freezing of a wet material containing water molecules and a substance other than water molecules, freeze concentrating of the substance in the wet material is to be inhibited, when in the freezing of a wet material containing a physiologically active substance, deactivation of the physiologically active substance is to be inhibited, and when through freezing or lyophilization of a wet material containing water molecules and a component other than water molecules, it is intended to produce a lyophilizate or frozen matter having the component homogeneously diffused therein, an antifreeze protein is added to the wet material.
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