| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6043bdb0b01c451f7cb26a35398ee03f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c090339464e2fec9b0fce1caf512e394
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_364e8e2ce683f466f0fd4651f7b3cbd7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc5eb799d55b8727ae86284e170d62d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7d3becc4cc108492354ae7b3c73d2b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1df29df8ecbc81c8a88da2cd70bbb1cb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1016 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2004-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18daaccc009fffe72877079ad6ee4d3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc31aed4f110585cc126656a1c2ca73b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7358bb38a63001526657a2a5da9f189
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c52f79c7b17fc68aa1bdd94e05e29c94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad06df8567ede91f049fdfb80f378f51 |
| publicationDate |
2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004075830-A3 |
| titleOfInvention |
Knockout identification of target-specific sites in peptides |
| abstract |
The invention provides methods for identification and determination of target-specific sites in peptides and proteins, including a method for determining the primary sequence of a secondary structure within a known parent polypeptide that binds to the target of interest. In one embodiment of the invention, a residue or mimetic containing a nitrogen atom and a sulfur atom available for binding to a metal ion is serially substituted for single residues in or inserted between adjacent residues in a known primary sequence of a peptide or protein. The resulting sequence is complexed with a metal ion thereby forming a metallopeptide. The resulting metallopeptides are then used in binding or functional assays related to the target of interest, and the metallopeptide(s) which result in significant or substantially decreased or changed binding or functionality are determined to identify the primary sequence involved in such binding or functionality. |
| priorityDate |
2003-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |