Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_789ff5758411a31ded99ce996e9142fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dcf0275e6c17e77579d95897dbfe964 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_723d67cc27bf0e0d208f61e7cb04cc6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_992d8e2b644ab21260ad23fb868613b0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 |
filingDate |
2004-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_756d5b628f71960e6c625e9cd7b6505c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5248fa36e23ddb226d5eb0003856fb3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0a66a92865d37bb43c3c1de120c47ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737a57bbbbf131a8b6ef0d3a608added |
publicationDate |
2004-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004073650-A2 |
titleOfInvention |
Peptidomimetic inhibitors of stat3 activity and their medical uses |
abstract |
The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics that inhibit STAT function. Peptidomimetics of the invention include dipeptides of the formula RY*L (where Y* represents phosphotyrosine), with the R group at the Y-1 position and L=Leu, Val, Ala or a non-polar amino acid. R is preferably aryl or heteroaryl, eventually substituted with halogens, amino and nitro groups. Peptidomimetics of the invention disrupt Stat3 activation and function. Peptidomimetics of the invention significantly inhibit tumor cell growth and induce tumor cell death. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016116603-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7951374-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012078982-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012078982-A2 |
priorityDate |
2003-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |