| abstract |
The present invention provides amlodipine cyclamate, a novel pharmaceutically acceptable acid addition salt of amlodipine, which is a potent and long-acting calcium channel blocker useful as an anti-ischemic or anti-hypertensive agent. Amlodipine cyclamate, which may be prepared by reacting amlodipine with cyclamic acid, has pharmacologically excellent properties such as low toxicity, and high stability, solubility, non-hygroscopicity, and processability. |