| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d58b729f5053ba803d6880d5f37b0c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d77e2d03d848c800b467f501f74b2698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9c129db85bf2ac7345750cfbe545ae1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06de984d7b40cc42714481fdcc440827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dcf2bea0ccec557cff9ff8005c65c97
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ace32fcbb7b3b918f5b5c3347094722c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dd62f55366e233d884953ac30e2a041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be5ef49fe6a70f922e214f2185877494
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee6175254df3db518608a5102a7ef2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_584d2a4c4473deaf014c807ffb4b2413 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2004-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e09119785e2edf2811502355470e1743
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a21bde4a4eb1cff4ffa73c848ec995bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4645bff626d65915b28f74c582176790
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb010ea457ac3b2000f69b43c3eb9558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889b418ba074abc25965de506a8e374a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4439b055449aeba2d5e83abe471f622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b718eda31d2bdad41fce98c97c568624
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6354327bcdf2de7a067fe9131ee10b3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bdbff79663a10c35fd840cbd3c1fd14 |
| publicationDate |
2004-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004067740-A1 |
| titleOfInvention |
Method and device for the detection of mutations in isolated gene sequences of the low-density lipoprotein receptor (ldl-r) which is associated with familial hypercholesterolemia |
| abstract |
The invention relates to extracorporeal methods of analysing the presence or absence of mutations which cause familial hypercholesterolemia. The inventive methods describe the way in which said mutations can be detected using a DNA sample from an individual and comprising the following: chain reaction of the polymerase with primers which are complementary to the low-density lipoprotein receptor gene; analysis of the amplified product by sequencing; restriction analysis; single strand conformation polymorphism techniques; heteroduplex analysis and analysis of a device on top of a biochip glass support on which oligonucleotide probes are disposed, which can be used to detect the aforementioned mutations in the DNA. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011003921-A2 |
| priorityDate |
2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |