http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004067050-A1
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f81860599dca189795b4a7e136a866c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51ab239e3066f1aabdf0757767588d99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3526ea18858a8903a69adfaadd309346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49283e0eb530fc43cd926f85782dd83c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2230-0065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-4646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-4649 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0011 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 |
filingDate | 2004-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd2e3b32a298ae56edd5dff90e2aec51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0ce9ca06c6de93a92736962fd2ed296 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_083323781e702cef04169f4da3a3f612 |
publicationDate | 2004-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2004067050-A1 |
titleOfInvention | Tissue pathogen inactivation/removal process |
abstract | Bone such as cortical or cancellous bone or connective tissue are centrifuged as a solution is applied to the tissue in a continuous process. The centrifuge creates forces, which cause the flowing solution to penetrate substantially all of the cavities of the tissue. The solution, which may be alcohol, a detergent, an oxidizer, or a surfactant, with or without water, flushes the cavities of the tissue and removes and inactivates viral and bacterial contaminants. In a second embodiment, bone or connective tissue is centrifuged in a batch process to remove contaminants from cavities in the tissue by first spinning the tissue dry and then submerging the tissue in a viral/bacteria cleansing solution and centrifuging the submerged tissue and solution at a sufficiently high speed and radius from the spin axis to create substantially high G forces on the tissue and solution to force the solution into and through the tissue cavities. The solution with the flushed contaminants is then removed from the vicinity of the tissue. In a further embodiment, an enzyme is centrifuged with the tissue to digest lipids and proteins which are then removed with a flushing solution which may also inactivate viral and bacterial contaminants. In yet a further embodiment, the centrifuge can be used to infuse biologically and/or structurally useful materials into the tissue. Further, the lipids and proteins may be removed by a chemically active agent such as oxo anions. |
priorityDate | 2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1721.