Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e950217383b321d9ca1bf6ad6e0ad97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b74695f4c6259a8598b722c1ef6eefa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ade54b5c85872c3dc5489e1488b7ec2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b30d029e17a58b678146d415d8936b46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdfdfc9b260e078966d7ec373bfbb43e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5435e4edaf844a911ce466ecc0d4d78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e44d187dd173dfc0ae3e843332abe23 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2004-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5846e9a41bfb6a93439f76b3534dbf89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39d938853e1294a670148c025c2ec20d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c796512849efa1daa5a90ba4f33a59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cfbaf4739f1b27400e5c67caeb86213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0659c70e40bba6d714bfea46d7fd6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be0f9a718a15dfde24c436a4640c4849 |
publicationDate |
2004-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004065602-A1 |
titleOfInvention |
Method of identifying the epithelial-mesenchymal transition of mesothelial cells (emtmc) and identifying emtmc-modulating compounds, pharmaceutical compositions and use thereof in the diagnosis and treatment of diseases associated with emtmc |
abstract |
The invention relates to a method of identifying the epithelial-mesenchymal transition of mesothelial cells (EMTMC) and identifying EMTMC-modulating compounds, pharmaceutical compositions and use thereof in the diagnosis and treatment of diseases associated with EMTMC. The inventive method is based on the fact that mesothelial cells play an active role in the structural and functional alteration of the peritoneum during peritoneal dialysis which leads to the epithelial-mesenchymal transition which in turn causes ultrafiltration failure. The aforementioned findings demonstrate a series of targets and markers which are intended for the development of novel peritoneal dialysis solutions, for the monitoring of patients undergoing said treatment and for the treatment of diseases associated with functional alterations to the mesothelium. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2310434-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093011-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8048621-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017042253-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108449998-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2310469-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9244058-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108449998-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7939272-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8377636-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8383357-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896730-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007082967-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008107508-A1 |
priorityDate |
2003-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |