| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ae443e43379713f9bf5a44abbc895ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ae81362f74a41a98b323a40dcd6d002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b156c4c7b598bb473a4679499f3e9a8a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba6b8212164be64c66fb3d013a151309 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2004-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54246fc4dcb99c4fa6dc2a5b3d486cd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_425ed2ac1b1f47b6c06581be88438c00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b3d74b9354a4eff6a32ea813c43ba6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5620d1a9832c42301fb8269f496d6af5 |
| publicationDate |
2004-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004065552-A2 |
| titleOfInvention |
Cell-based therapies for diabetes mellitus and other glucose intolerant states |
| abstract |
The present invention provides cells comprising an isolated nucleic acid encoding a novel lactate dehydrogenase (LDH) and/or the encoded LDH polypeptide. The invention further provides cells comprising an isolated nucleic acid encoding LDH, wherein the cell is capable of producing and secreting insulin. Also provided are methods of providing fuel-stimulated (e.g., glucose-stimulated) insulin secreting capability to a mammalian subject by implanting cells of the invention (e.g., in a semi-permeable membrane and/or an implantable device) into the subject. Further provided are devices comprising the cells of the invention. In particular embodiments, the device is an implantable device. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8071357-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9150835-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007043253-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3255149-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2537935-A3 |
| priorityDate |
2003-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |