| abstract |
An antibody which has an extremely high avidity to human ZAQL-1, can neutralize the activity of human ZAQL-1 and inhibits the function of human ZAQL-1. Owing to these characteristics, this antibody is useful as a preventive, a remedy or a diagnostic for, e.g., digestive diseases, diseases associated with angiogenesis, diseases relating to pregnancy, eating disorder, sleeping disorder, seasonal depression, reproductive dysfunction, endocrine diseases, senile dementia, Alzheimer’s disease, various disorders caused by aging, cerebral circulatory disorder, head trauma, spinal injury, epilepsy, anxiety, depression, manic depression, schizophrenia, alcoholism, Parkinson’s disease, hypertension, arteriosclerosis, arrhythmia, premenstrual disorder syndrome, glaucoma, cancer, AIDS, diabetes, etc. |