| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95a22228273850f2f751eb644cc32a91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d48e124118c791977c1ca9afdd464e9b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-48 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-48 |
| filingDate |
2004-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a139081a5c8db55ecd972550e2fd6186 |
| publicationDate |
2004-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004061091-A2 |
| titleOfInvention |
Insulin producing cells |
| abstract |
The present invention relates to a method for modifying liver cells such that they produce and store insulin. In addition, the invention relates to these modified cells and their use in the treatment of insulin-dependant diabetes. Accordingly the present invention provides a modified human hepatic cell characterised in that said cell is insulin-producing. In addition, the present invention provides a method for making an insulin-producing cell line comprising the steps of: (i.) isolating human hepatic progenitor cells; (ii.) introducing a construct for expressing Pdx 1 into said cells; and (iii.) selecting and isolating cells which express Pdx 1. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010090758-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006015209-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006015209-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010090758-A2 |
| priorityDate |
2003-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |