Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709b4a26ef028713f9b302509eb824d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04cd15b8fd5093ff3de3e45d4fa7b07b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-84 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 |
filingDate |
2003-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abdcfd9f981fa2e6800b074de7fde234 |
publicationDate |
2004-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004058982-A2 |
titleOfInvention |
Asymmetric reductive amination of ketones |
abstract |
Processes for the preparation of compounds having a chiral carbon substituted with an amine are disclosed. The processes include admixing a ketone with an amine in the presence of a catalyst having a chiral phosphine ligand and an acid. The admixture can also contain a reducing additive. The admixture is then exposed to hydrogen to directly and asymmetrically aminate the ketone. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007104359-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3301087-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018060512-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110551035-A |
priorityDate |
2002-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |