| abstract |
A benzocycloheptapyridine compound represented by the following general formula (I), which has an excellent antagonism to leukotriene D4, as well as an antagonism to leukotriene C4 and an antagonism to leukotriene E4 and is useful as an antiallergic agent and an antiinflammatory agent, and its pharmacologically acceptable salt: (I) wherein A represents a heterocyclic aromatic group, etc.; B represents -CH=CH-, etc.; D and E represent each carbon, etc.; X represents oxygen, etc.; Y represents optionally substituted alkylene, etc.; and Z represents optionally protected carboxyl, etc. |