abstract |
The present invention is directed to a neutrokine-alpha conjugate, wherein saidneutrokine-alpha conjugate comprises a neutrokine-alpha protein and a chelator. The present invention is also directed to a neutrokine-alpha complex, wherein saidneutrokine-alpha complex comprises a neutrokine-alpha conjugate and a metal ionwherein said metal ion is noncovalently associated with the chelator of saidconjugate. The present invention is further directed to compositions, specificallypharmaceutical and diagnostic compositions, comprising a neutrokine-alphaconjugate or complex as described herein. Therapeutic and diagnostic uses of saidconjugate, complex, and compositions are described. |