Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48242bfd53775e84753a31ba6ce731e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1e53d1c22ee74a2103c549034a07b1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f94c800eba8f7b481178914ca20226cb |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1688 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate |
2003-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c220446bb69dbcc1997b8f1ac2fbceb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda5fb815f784827f09a0e0f58d40ca2 |
publicationDate |
2004-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004058222-A1 |
titleOfInvention |
High pressure compaction for pharmaceutical formulations |
abstract |
Methods for producing a pharmaceutical preparation of pressure-fused particles including an active pharmaceutical ingredient are disclosed. The methods include the application of a pressure of between 0.1 GPa and 10 GPa to produce a compacted sample. The pressure-fused particles of the invention are useful for parenteral administration, and particularly sustained-release formulations, due to dissolution kinetics which are superior to conventional crystalline or amorphous packed powder preparations of active pharmaceutical ingredients. Pharmaceutical preparations including such pressure-fused microparticles are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10363224-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652527-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1965773-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11219604-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172878-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007049304-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9555005-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9101545-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11351124-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007049304-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889190-B2 |
priorityDate |
2002-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |