| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_918a9db0ce83eb611b7572d90fc1226a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_693f6788bb1a4170c1c1aebb80c7ad0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9197a31f9d38e34bf9fa8e2c576a50bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b177c026705d1835aa24fef6f10b946 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-02004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate |
2003-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f3590f15383ba3abb2919a9e99eccdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e446a4323aa5c8a480c35950016a0a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9609b78205999d48d1d43a1adc673959 |
| publicationDate |
2004-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004058147-A2 |
| titleOfInvention |
Human chondroitinase glycoprotein (chasegp), process for preparing the same, and pharmaceutical compositions comprising thereof |
| abstract |
The invention relates to the discovery of a novel Chondroitinase Glycoproteins (CHASEGP's), methods of manufacture, and potential uses in conditions where removal of chondroitin sulfates may be of therapeutic benefit. Chondroitinase Glycoproteins require both a substantial portion of the catalytic domain of the CHASEGP polypeptide and asparagine-linked glycosylation for optimal chondroitinase activity. The invention also includes carboxy-terminal deletion variants of CHASEGP that result in secreted variants of the protein to facilitate manufacture of a recombinant CHASEGP. Further described are suitable formulations of a substantially purified recombinant CHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity. CHASEGP is useful for the degradation of glycosaminoglycans and chondroitin sulfate proteoglycans under clinical conditions where their removal is of therapeutic value. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009128917-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723959-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815558-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10328130-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2009236635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10301376-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2662090-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I395593-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE47761-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3192525-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10286044-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8853369-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7544499-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9775889-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9677061-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833498-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013201899-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009111083-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009128917-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102065886-A |
| priorityDate |
2002-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |