abstract |
The present invention relates to methods and dosage forms for reducing and/or preventing the incidence of cardiovascular disease, including heart attacks, in individuals who are at risk, such as those individuals suffering from hypertension. The treatments and dosage forms of the present invention concern the administration of a diuretic, such as a thiazide diuretic like ThalitoneĀ®, either alone or in combination with an ACE-inhibitor, such as ramipril or ramiprilat like AltaceĀ®, to reduce and/or prevent the incidence of cardiovascular disease, namely, heart attacks or failure, in individuals who suffer from hypertension or are at risk. |