| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a3bfa8b131f3c4f9cf1c38d3d68b662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f5208e2e28ffa7cd2a7c8981b1cbfeb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-064 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M11-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-217
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 |
| filingDate |
2003-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87d4b733a2bc81cc8498df01cab6ec18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbc8021796989b017ca181d61a353eed |
| publicationDate |
2004-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004054605-A1 |
| titleOfInvention |
Freeze-dried interferon-ϝ composition for transpulmonary administration and inhalation system therefor |
| abstract |
The present invention provides a freeze-dried interferon-Ϝ composition for transpulmonary administration which can maintain IFN-Ϝ stably, and can be prepared into fine particles in a vessel at the time of use. A freeze-dried interferon-Ϝ composition for transpulmonary administration of the present invention has the following properties (i) to (iv): (i) containing at least one hydrophobic stabilizer selected from the group consisting of hydrophobic amino acids, dipeptides of hydrophobic amino acids, tripeptides of hydrophobic amino acids and derivatives of hydrophobic amino acids and salts thereof; at least one hydrophilic stabilizer selected from the group consisting of hydrophilic amino acids, dipeptides of hydrophilic amino acids, tripeptides of hydrophilic amino acids, derivatives of hydrophilic amino acids and salts thereof; and interferon-Ϝ (ii) a non-powder cake-like form; (iii) a disintegration index of 0.015 or more; and (iv) becoming fine particles having a mean particle diameter of 10 microns or less or a fine particle fraction of 10% or more upon receipt of an air impact having an air speed of at least 1 m/sec and an air flow rate of at least 17 ml/sec. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108310557-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10307464-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10130685-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10143655-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10258664-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10046031-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009513682-A |
| priorityDate |
2002-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |